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at the target of interest.
* Nebulization forces DNA through a small hole in a nebulizer unit, which results in the formation of a fine mist that is collected. Fragment size is determined by the pressure of the gas used to push the DNA through the nebulizer, the speed at which the DNA solution passes through the hole, the viscosity of the solution, and the temperature.
* Sonication, a type of hydrodynamic shearing, subjects DNA to acoustic cavitation and hydrodynamic

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