Thomas Guy was entombed at the hospital's chapel (also dating from the 18th century), in a tomb featuring a marble sculpture by John Bacon.

The original buildings formed a courtyard facing St Thomas Street, comprising the hall on the east side and the chapel, Matron's House and Surgeon's House on the west side. The original main buildings were built by the King's Master Mason, John Deval, in 1739.

A bequest of £180,000 by William

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