P₄O₆ is converted into the mixed P(III)P(V) species P₄O₈ when heated in a sealed tube at 710 K, with the side product being red phosphorus.

As a ligand

P₄O₆ is a ligand for transition metals, comparable to phosphite. An illustrative complex is P₄O₆·Fe(CO)₄. With BH₃, a dimeric adduct is produced:
:

References