BRCA2, PALB2 and RAD52.

The structural basis for Rad51 filament formation and its functional mechanism still remain poorly understood. However, recent studies using fluorescent labeled Rad51 have indicated that Rad51 fragments elongate via multiple nucleation events followed by growth, with the total fragment terminating when it reaches about 2 um in length. However, disassociation of Rad51 from dsDNA is slow and incomplete, suggesting that there