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<p>potentials are generated by special types of <a href="page.php?w=voltage-gated_ion_channel">voltage-gated ion channel</a>s embedded in a cell's <a href="page.php?w=plasma_membrane">plasma membrane</a>. These channels are shut when the membrane potential is near the (negative) <a href="page.php?w=resting_potential">resting potential</a> of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold voltage, "<a href="page.php?w=depolarization">depolarising</a>" the membrane. When the channels open,</p><p>
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