The most common application is the separation of solid from highly concentrated suspensions, which is used in the treatment of sewage sludges for dewatering where less consistent sediment is produced.

The centrifugation method has a wide variety of industrial and laboratorial applications; not only is this process used to separate two miscible substances, but also to analyze the hydrodynamic properties of macromolecules. It is one of the most important and commonly used research methods in biochemistry,