can be used to release biologically active compounds under specific conditions. In most cases the mechanism of controlled degradation of such complexes is based on pH change of water solutions, leading to the loss of hydrogen or ionic bonds between the host and the guest molecules. Alternative means for the disruption of the complexes take advantage of heating or action of enzymes able to cleave ?-1,4 linkages between glucose monomers. Cyclodextrins were also shown to enhance mucosal penetration of drugs.

Chromatography