(A-J) and forty subgenotypes according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment. The serotypes and genotypes do not necessarily correspond.

The ape-infecting HBVs are placed in between human HBV genotypes. The different genotypes show evidence of recombination.

Morphology

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