to increase the synaptic output of the involved motor neuron which in turn increases the motor output of the involved muscles and, thus, decreases functional impairment. As the amount of intermittent hypoxia changes the amount of serotonin release and, as a result, the amount of LTF, this process exhibits metaplasticity. Metaplasticity occurs when the LTF is itself plastic or variable.

Intermittent hypoxia-induced LTF has also been demonstrated in carotid denervated rats, suggesting that synaptic