to be due to human ingestion of BSE-tainted cattle products.

Gene

The human PRNP gene is located on the short (p) arm of chromosome 20 between the end (terminus) of the arm and position 13, from base pair 4,615,068 to base pair 4,630,233.

Structure

PrP is highly conserved in mammals, lending credence to conclusions derived from experimental animals such as mice. In primates, PrP ranges from 92.9% to 99.6% similarity in amino acid sequences.

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