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<p>12.5 years (down from 12.6).</p>

<p><big>Physiology</big></p>
<p><big>Puberty</big></p>
<p>Menarche is the culmination of a series of <a href="page.php?w=physiological">physiological</a> and anatomic processes of <a href="page.php?w=puberty">puberty</a>:<br/>
* Attainment of a sufficient <a href="page.php?w=body_fat_percentage">body fat percentage</a> (typically around 17% of total body mass).<br/>
* Disinhibition of the <a href="page.php?w=GnRH">GnRH</a> pulse generator in the <a href="page.php?w=arcuate_nucleus">arcuate nucleus</a> of the <a href="page.php?w=hypothalamus">hypothalamus</a>.<br/></p><p>
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