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<p>was mixed with about 16% <sup>239</sup>Pu.</p>

<p><big>Manhattan Project</big></p>
<p>Plutonium was first synthesized in 1940 and isolated in 1941 by chemists at the University of California, Berkeley.</p>

<p>The <a href="page.php?w=Manhattan_Project">Manhattan Project</a> began shortly after the discovery, with most early research (pre-1944) carried out using small samples manufactured using the large <a href="page.php?w=cyclotron">cyclotron</a>s at the Berkeley <a href="page.php?w=Lawrence_Berkeley_National_Laboratory">Rad Lab</a> and <a href="page.php?w=Washington_University_in_St._Louis">Washington University in St. Louis</a>.</p><p>
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