to convert the terminal glycine to an amine group (releasing glycolate). After this step, the transformation from the precursor protein proIAPP to the biologically active IAPP (amylin) is complete (IAPP sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2).

Regulation

Insofar as both IAPP and insulin are produced by the pancreatic ?-cells, impaired ?-cell function (due to lipotoxicity and glucotoxicity) will affect

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