1544 to Wolfgang, Count Palatine of Zweibrücken.
# William IV of Hesse-Kassel (or Hesse-Cassel) (24 June 1532 – 25 August 1592).
# Philipp Ludwig (29 June 1534 – 31 August 1535), died in infancy.
# Barbara of Hesse (8 April 1536 – 8 June 1597), married:
## in Reichenweier on 10 September 1555 to