was originally designed in the Computer Systems Laboratory (CSL), a branch of the Xerox Palo Alto Research Center, for the Alto, an experimental micro-coded workstation. Initially, its spread was confined to PARC and a few universities to which Xerox had donated some Altos.

Mesa was later adopted as the systems programming language for Xerox's commercial workstations such as the Xerox 8010 (Xerox Star, Dandelion) and Xerox 6085 (Daybreak),