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of complex subcellular machinery, and the convergent emergence of several typical microbial morphologies.

Origins

While some scientists, such as Freese (1962) and Freese and Yoshida (1965), had suggested that neutral mutations were probably widespread, the original mathematical derivation of the theory had been published by R.A. Fisher in 1930. Fisher, however, gave a reasoned argument for believing that, in practice, neutral gene substitutions would be very

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