for Pomponia to marry his younger brother Quintus Tullius Cicero. Quintus and Pomponia married in 68 BC. Pomponia bore Quintus a son of the same name.

Quintus and Pomponia had a long unhappy marriage and they constantly quarrelled. Pomponia was a woman of strong character. Their constant quarrelling greatly upset Cicero and he mentioned this in his letters to Atticus. Cicero tried to assist his sister-in-law and his brother to resolve their problems, but Cicero naturally supported his brother.