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study - that pre-ejaculate may contain sperm that can cause pregnancy, which is a common basis of argument against the use of coitus interruptus (withdrawal) as a contraceptive method.

Studies have demonstrated the presence of HIV in most pre-ejaculate samples from infected men.

Overproduction

In rare cases, an individual may produce an excessive amount of pre-ejaculate fluid, which may be treatable by a 5-alpha-reductase inhibitor,

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