1.Previous
3.Next

The most general form for the reaction may be given as
:Nuc\mathbf{:}- + R-LG -> R-Nuc{} + LG\mathbf{:}-where indicates the substrate. The electron pair (:) from the nucleophile (Nuc:) attacks the substrate , forming a new covalent bond . The prior state of charge is restored when the leaving group (LG) departs with an electron pair. The principal product in this case is . In such reactions, the nucleophile is usually electrically neutral or negatively charged, whereas the substrate

1.Previous
3.Next