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cell syncytium. Syncytin-1 expression on the surface of cytotrophoblasts and syncytiotrophoblast mediate fusion. The syncytiotrophoblast layer is the interface between the developing fetus and the maternal blood supply, which forms, together with the underlying basal membrane and the fetal endothelium the placental barrier. The placental barrier enables nutrient and waste exchange, while blocking maternal immune and other cells,

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