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In those with cardiac arrest or cardiogenic shock, it is believed to improve survival and good outcomes. However, a recent clinical trial has shown that in patients with cardiogenic shock following acute myocardial infarction, ECLS did not improve survival (as measured via 30-day mortality); on the contrary, it resulted in increased complications (e.g., major bleeding, lower limb ischemia). This finding is corroborated by a recent meta-analysis that used data from four previous clinical trials, indicating a need to reassess current guidelines

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