and a better understanding of these forces would help to explain why gastroschisis occurs mostly to the right of the umbilicus, while other ventral body wall defects occur in the midline.

At least six hypotheses have been proposed for the pathophysiology:
# Failure of mesoderm to form in the body wall
# Rupture of the amnion around the umbilical ring with subsequent herniation of bowel
# Abnormal involution of the right umbilical vein leading to weakening of the body wall and gut herniation