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in the clotting system, which in turns stimulates thrombin production. Thrombin also causes platelet aggregation.

As such, more often than not, platelet adhesion and activation occur in overlapping steps, where one directly influences and contributes to the other.

Platelet adhesion

Once platelets are activated, when they come across injured endothelium cells, the von Willebrand factor (vWF) and fibrinogen will act as anchors to allow

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