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<p>and <a href="page.php?w=Republic_of_Venice">Venetian</a> merchants to <a href="page.php?w=Europe">Europe</a> until the rise of the <a href="page.php?w=Seljuk_Turks">Seljuk Turks</a> in 1090. Later the <a href="page.php?w=Ottoman_Turks">Ottoman Turks</a> held the route again by 1453 respectively. Overland routes helped the spice trade initially, but maritime <a href="page.php?w=trade_route">trade route</a>s led to tremendous growth in commercial activities to Europe. </p>

<p>The trade was changed by the <a href="page.php?w=Crusades">Crusades</a> and</p><p>
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