volumes. In this case, a normalization of the detectors is absolutely needed. To normalize the detectors, a measurement of a pure solvent is made first. Then an isotropic scatterer is added to the solvent. Since isotropic scatterers scatter the same intensity at any angle, the detector efficiency and gain can be normalized with this procedure. It is convenient to normalize all the detectors to the 90° angle detector.

where I_R(90) is the scattering intensity measured for the Rayleigh scatterer by the 90° angle detector.

The

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