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<p>(<i>?????</i>, Shanghán Zábìng Lùn), compiled by <a href="page.php?w=Zhang_Zhongjing">Zhang Zhongjing</a> near the end of the <a href="page.php?w=Han_dynasty">Han dynasty</a> (c.&nbsp;196-220&nbsp;CE). It is the first medical text that organized therapeutic principles around the diagnosis of symptom patterns (, <i>?</i>), and it combined <a href="page.php?w=Yin_and_yang">Yinyang</a> and <a href="page.php?w=Wuxing_%28Chinese_philosophy%29">Five Phases</a> theory with specific medicinal prescriptions. After passing through numerous changes,</p><p>
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