1.Previous
3.Next

fluorescence photo-bleaching to visualize polypeptide hormone-receptor complexes bound to the membrane of living cells. He showed these complexes were highly mobile and clustered before entry into cells, and measured their lateral diffusion coefficients. In collaboration with Mark Willingham, he developed and used video intensified microscopy to visualize fluorescently labeled insulin and EGF forming clusters on the surface of living cells prior to entry through the endocytic pathway. These studies identified the pathway by which growth factors

1.Previous
3.Next