This reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase (GAPDH).

Glycogen synthesis

The phosphorylation of glucose to glucose 6-phosphate has role in regulating glycogen synthase.

Glucose is phosphorylated to glucose 6-phosphate to allow its transport across the membrane by ATP-D-glucose 6-phosphotransferase and non-specific hexokinase

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