1.Previous
3.Next

in fibrin. The covalent bonds increase the stability of the fibrin clot. Thrombin interacts with thrombomodulin.

As part of its activity in the coagulation cascade, thrombin also promotes platelet activation and aggregation via activation of protease-activated receptors on the cell membrane of the platelet.

Negative feedback

Thrombin bound to

1.Previous
3.Next