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<p>of bone marrow edema is difficult due to the vast variety of causes, but detecting bone marrow edema can predict subsequent progression to bone erosion or the need to replace the joint.</p>

<p><big>Signs and symptoms</big></p>
<p>Common symptoms of BME include <a href="page.php?w=joint_effusion">joint effusion</a>, <a href="page.php?w=Arthralgia">joint pain</a>, and warmth, which are related to joint <a href="page.php?w=inflammation">inflammation</a>. Patients usually have severe pain in the bones or joints, which often leads to limitations in functionality</p><p>
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