The server IO die is able to serve as a hub to connect up to eight 8-core chiplets, while the IO die for Matisse is able to connect up to two 8-core chiplets. These chiplets are linked by AMD's own second generation Infinity Fabric, allowing a low-latency interconnect between the cores and to IO. The processing cores in the chiplets are organized in CCXs (Core Complexes) of four cores, linked together to form a single eight core CCD (Core Chiplet Die).

Zen 2 also powers a line of mobile and desktop APUs marketed as Ryzen 4000,