Binding to its receptor

The docking of IP₃ to its receptor, which is called the inositol trisphosphate receptor (InsP3R), was first studied using deletion mutagenesis in the early 1990s. Studies focused on the N-terminus side of the IP₃ receptor. In 1997 researchers localized the region of the IP₃ receptor involved with binding of IP₃ to between amino acid