of Medicinal Chemistry. During the 1990s, the anti-cancer properties of tocopherols and tocotrienols began to be delineated. The current commercial sources of tocotrienol are rice bran oil and palm oil. Other natural tocotrienol sources include barley and oats. Tocotrienols are safe and human studies show no adverse effects with consumption of 240 mg/day for 48 months.

The discovery of vitamin E by scientists Katherine Bishop and Herbert Evans in 1922 marked the beginning of the understanding