unlike in other skin diseases, this can be caused by daily activities, especially chronic friction on particular areas of the body. The phenomenon occurs in a third of patients with nonsegmental vitiligo (NSV) but is rarely seen in segmental vitiligo (SV).

Existing cases of vitiligo may also be aggravated by temperature changes (causing dryness or sweating), poor hydration, or unprotected sun exposure.

Immune

Variations in genes that are expressed

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