European population were significantly contributing factors to the inspiration and solidification of the Dance of Death tradition in the fourteenth century. In her thesis, The Black Death and its Effect on 14th and 15th Century Art, Anna Louise Des Ormeaux describes the effect of the Black Death on art, mentioning the Danse Macabre as she does so:

Some plague art contains gruesome imagery that was directly influenced by the mortality of the plague or by the medieval fascination with the macabre and awareness of death that were augmented by the plague. Some plague art documents psychosocial responses to the fear that plague aroused in its victims. Other plague art is of a subject that directly responds to people's reliance on religion to give them hope.