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<p>also discourage the use of nightshades because of the alkaloid <a href="page.php?w=solanine">solanine</a> which is thought to affect calcium balance. Some proponents of a macrobiotic diet believe that nightshade vegetables can cause <a href="page.php?w=inflammation">inflammation</a> and <a href="page.php?w=osteoporosis">osteoporosis</a>.</p>

<p><big>History</big></p>
<p>Macrobiotics was founded by George Ohsawa and popularized in the United States by his disciple Michio Kushi. In the 1960s, the earliest and most strict variant of the diet was termed</p><p>
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