The team's first confirmed collaboration was on the six-page "Wylie's Wild Horses" in Hillman Periodicals' Western Fighters vol. 2, #12 (Nov. 1950), signaling the start of a four-decade collaboration.

They quickly founded their own comics-book company, the name of which is variously rendered as MR Publications, the combined initials of their first names; Mr. Publications, after the company's sole series, the whimsical adventure comic Mister Universe, which ran five issues (July 1951 - April