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Functional isomers are structural isomers which have different functional groups, resulting in significantly different chemical and physical properties.

An example is the pair propanal H₃C-CH₂-C(=O)-H and acetone H₃C-C(=O)-CH₃: the first has a -C(=O)H functional group, which makes it an aldehyde, whereas the second has a C-C(=O)-C group, that makes

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