pathway and subsequent activation of PLC ?2 and the TRPM5 channel in these taste cells functions to activate the cell.

Location and innervation

TAS1R1+3 expressing cells are found mostly in the fungiform papillae at the tip and edges of the tongue and palate taste receptor cells in the roof of the mouth. These cells are shown to synapse upon the chorda tympani nerves to send their signals to the brain, although some activation of the glossopharyngeal nerve

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