channel in healthy kidney function remain less understood. Podocytes normally display minimal baseline activity of TRPC6 channels and TRPC6 knockout mice have not shown any evident changes in glomerular structure or filtration.

Nevertheless, it has been hypothesized that the function of TRPC6 channels in podocytes resembles their function in smooth muscles of blood vessels.

Glomerular capillaries operate under significantly higher pressure than most other capillary beds. When podocytes are

1.Previous
3.Next