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include difficulty breathing, wheezing (a whistling sound when you breathe), and chest pain. Exacerbations of symptoms may occur; these exacerbations occur more frequently in advanced or severe disease. Systemic symptoms, including fevers, chills, night sweats, fatigue and weight loss may be seen with bronchiectasis. Bronchiectasis may also present with coughing up blood in the absence of sputum,

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