1.Previous
3.Next

is a neurotoxin. It acts as an antagonist of the nicotinic acetylcholine receptor (nAChR) by physically blocking an open ion channel, leading to hyperpolarization of the neuron.Nagata et al. studied the effects of dioscorine on the nicotinic acetylcholine receptor in rat clonal phaeochromocytoma cells (mixture of neuroblasts and eosinophils). They found that dioscorine at concentrations of 0.45-450 uM accelerated the desensitization of current induced

1.Previous
3.Next