than they are with pathological states. They function alongside osteoblasts to remodel and maintain the integrity of bones in the body. They also contribute to the creation of the niche necessary for hematopoiesis and negatively regulate T cells. However, while the primary functions of osteoclasts are integral to maintaining a healthy physiological state, they have also been linked to osteoporosis and the formation of bone tumors.

Giant cell arteritis

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