that cardiac pathologies are more prevalent in patients with pathological evidence of cerebrovascular SVD and vice versa.

Coronary microvascular diseases (CMDs) can be caused by:

On the other hand, Cerebral SVD encompasses a range of vascular pathologies including arteriosclerosis-related CSVD, where lipohyalinosis causes stenosis of the lumen of the arterioles and amyloid-related CSVD, characterized by the build-up of ?-amyloid deposits in small- and medium-caliber cerebral vessels.

The

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