the italic= in 1625 (Galileo had called it the occhiolino 'little eye'). René Descartes (Dioptrique, 1637) describes microscopes wherein a concave mirror, with its concavity towards the object, is used, in conjunction with a lens, for illuminating the object, which is mounted on a point fixing it at the focus of the mirror.

Rise of modern light microscopes

The first detailed account of the microscopic anatomy of organic tissue based on the

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