penetrate the membranes. While the two membranes and the endoplasmic reticulum are linked, proteins embedded in the membranes tend to stay put rather than dispersing across the continuum. It is lined with a fiber network called the nuclear lamina which is 10-40 nm thick and provides strength.

Mutations in the genes that encode for the inner nuclear membrane proteins can cause several laminopathies.

Nuclear pores

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