He was offered a research position at the MNI from Milner but chose instead to accept a professorship at the University of Lethbridge (U of L) where he could pursue his own research focusing on the comparative physiology of the rat and human diseases including Parkinson's Disease, Stroke and developmental disorders. He has remained at the U of L ever since.

Kolb is likely best known for his textbook, Fundamentals of Neuropsychology, as of 2019 in its seventh