nm in diameter under low-salt or experimentally reconstituted conditions.

In addition to core histones, a linker histone H1 binds near the entry and exit sites of DNA on the nucleosome and contributes to higher-order chromatin organization. The nucleosome core particle, together with histone H1, is known as a chromatosome.

The nucleosomes bind DNA non-specifically, as required by their function in general DNA packaging. There are, however, large DNA sequence

1.Previous
3.Next