and lungs are important to maintain the stability of blood pH. Therefore, carbonic anhydrase helps with the H+ secretion into the lumen of the renal tubule and the reabsorption of HCO₃^- in the kidneys. Also, it helps the carbon dioxide transport from the lung tissue to the alveoli in the pulmonary capillary, where the carbon dioxide will be excreted during exhalation.

Carbonic anhydrase is a very ancient enzyme found in both domains of prokaryotes that exists in six different classes