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There is very uncertain evidence supporting the use of prophylactic antibiotics to prevent endometritis after manual removal of the placenta in vaginal birth. Histologically, neutrophilic infiltration of the endometrial tissue is present during acute endometritis. The clinical presentation is typically high fever and purulent vaginal discharge. Menstruation after acute endometritis is excessive and, in uncomplicated cases, can resolve after 2 weeks of clindamycin and gentamicin

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